Latest Publications by Legacy Research Institute Scientists:

A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network. .
Lee PY, Hua Y, Brazile BL, Yang B, Wang L, Sigal IA.
J Biomech Eng. 2022 Jun 1;144(6):061006. doi: 10.1115/1.4054056.>
https://pubmed.ncbi.nlm.nih.gov/35266993

Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy.
Luo HY, Shen HY, Perkins RS, Wang YX.
Front Pharmacol. 2022 Jun 1;13:908882. doi: 10.3389/fphar.2022.908882.
https://pubmed.ncbi.nlm.nih.gov/35721189

Intraocular Pressure and Medication Burden With Cataract Surgery Alone, or Cataract Surgery Combined With Trabecular Bypass or Goniotomy. .
McNiel CL, Sanchez FG, Rees JP, Gardiner SK, Young JW, Kinast RM, Young A, Jones EP, Mansberger SL.
J Glaucoma. 2022 Jun 1;31(6):423-429. doi: 10.1097/IJG.0000000000002028.
https://pubmed.ncbi.nlm.nih.gov/35353775

Prolonged diet-induced obesity modifies DNA methylation and gene expression in the hippocampus.
Vander Velden JW, Osborne DM.
Neurosci Lett. 2022 May 29;780:136656. doi: 10.1016/j.neulet.2022.136656.
https://pubmed.ncbi.nlm.nih.gov/35469824

Variation in adoption of skin and nipple sparing mastectomy: An opportunity to enhance patient outcomes.
Wetzel CL, Gardiner SK, Johnson N, Garreau JR, Sutton TL.
Am J Surg. 2022 May 23:S0002-9610(22)00343-9. doi: 10.1016/j.amjsurg.2022.05.020. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35659767

Net gain and loss: influence of natural rewards and drugs of abuse on perineuronal nets.
Brown TE, Sorg BA.
Neuropsychopharmacology. 2022 May 14. doi: 10.1038/s41386-022-01337-x. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/35568740

Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice
Simon M, Wang MX, Ismail O, Braun M, Schindler AG, Reemmer J, Wang Z, Haveliwala MA, O'Boyle RP, Han WY, Roese N, Grafe M, Woltjer R, Boison D, Iliff JJ.
Alzheimers Res Ther. 2022 Apr 26;14(1):59. doi: 10.1186/s13195-022-00999-5.
https://pubmed.ncbi.nlm.nih.gov/35473943

A high-accuracy and high-efficiency digital volume correlation method to characterize in-vivo optic nerve head biomechanics from optical coherence tomography. .
Zhong F, Wang B, Wei J, Hua Y, Wang B, Reynaud J, Fortune B, Sigal IA.>
Acta Biomater. 2022 Apr 15;143:72-86. doi: 10.1016/j.actbio.2022.02.021.
https://pubmed.ncbi.nlm.nih.gov/35196556

Cataract Surgery Lowers Intraocular Pressure and Medication Use in the Medication Group of the Ocular Hypertension Treatment Study..
Mansberger SL, Gardiner SK, Gordon M, Kass M, Ramulu P; Ocular Hypertension Treatment Study group.>
Am J Ophthalmol. 2022 Apr;236:53-62. doi: 10.1016/j.ajo.2021.07.008.
https://pubmed.ncbi.nlm.nih.gov/34280363