COCCIDIOIDES ANTIBODIES PANEL BY ID
Coccidioides Abs Panel, by CF, ID, ELISA
For Coccidioides, immunodiffusion (ID) measures IgM antibodies, while complement fixation (CF) measures both IgG and IgM. ELISA tests can be used to detect both coccidioidal IgG and IgM antibodies. While elevated single antibody titers may be diagnostic, paired samples are preferred. Acute and convalescent samples drawn at least 21 days apart, showing a fourfold or greater rise in titer, are diagnostic. Negative fungal serology does not rule out the possibility of current infection.
Specimen Collection Requirements
Serum, one 4.0 mL gold (SST) top tube
Separate serum from cells ASAP. Parallel testing is preferred. Convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as Acute or Convalescent.
Other body fluids, severely lipemic, contaminated or hemolyzed specimens
AFTER SEPARATION FROM CELLS: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year, avoid repeated freeze/thaw cycles
Complement Fixation/Immunodiffusion/Enzyme-Linked Immunosorbent Assay
Thursday, January 5, 2017 03:42:04 AM