BUPRENORPHINE & METABOLITES
For medical purposes only; not valid for forensic use.
The presence of metabolite(s) without parent drug may indicate use of parent drug during the prior week.
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive.
Specimen Collection Requirements
One plain red, lavender (EDTA), or pink (K2EDTA).
Remove serum/plasma from cells ASAP
2 mL serum or plasma at 2-8°C. (Min: 1 mL) Submit specimen in an Standard Transport Tube
Specimens exposed to repeated freeze/thaw cycles. Separator tubes and plasma or whole blood from lt. blue tubes (sodium citrate).
After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years.
Liquid Chromatography-Tandem Mass Spectrometry
buprenorphine: 2 ng/mL
norbuprenorphine: 2 ng/mL
buprenorphine glucuronide: 5 ng/mL
norbuprenorphine glucuronide:5 ng/mL
Thursday, January 5, 2017 03:42:01 AM